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SphygmoCor Technology

The SphygmoCor System, provides the following capabilities:

• SphygmoCor Px Non-Invasive Aortic BP system, which non-invasively derives the calibrated BP waveform at the aortic root,
• SphygmoCor Vx Pulse Wave Velocity system, which measures the velocity of the BP pressure wave between any two superficial artery sites (and so gives a measure of arterial stiffness).
• SphygmoCor Mx Non-Invasive Aortic BP Monitoring system, which monitors the ascending aortic waveform continuously, including real time trending of key central heart function parameters.

The SphygmoCor Px system complements the traditional cuff sphygmomanometer by non-invasively providing the following previously unavailable central clinical information:

• Evaluation of arterial stiffness and its clinical impact on the heart in increasing patient risk of heart failure, stroke and myocardial ischaemia.
• Coronary artery perfusion pressure throughout the cardiac cycle, including during the critical period of diastole when over 95% of subendocardial perfusion occurs.
• Left ventricular load, systolic “afterload”, and an index of myocardial oxygen demand.
• Pulse pressure in the ascending aorta which drives cerebral blood flow - and hence a better indicator of the risk of stroke.
• Central systolic pressure (as seen by the baro-receptors), often markedly different from the cuff value.
• Ejection duration and other cardiac cycle timing parameters.
• A powerful index of subendocardial viability giving an indication of cardiac reserve and exercise tolerance.
• Efficacy of drug therapies on key central heart function parameters

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