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Andor Zyla 5.5 sCMOS Camera

Zyla 5.5 is a large field of view, high resolution 5.5 megapixel sCMOS camera, ideal for research and OEM usage. Zyla 5.5 offers a 100 fps frame rate and ultra-low noise performance, in a light, compact design. A highly cost-effective USB 3.0 version is available, offering industry fastest speeds up to 40 fps (full frame), representing the ideal performance upgrade for your lab. NEW GPU Express works alongside SDK3 to enable simplified and optimized data transfers from camera to GPU for real time processing.

True Global Exposure
Zyla 5.5 CMOS camera uniquely offers both Rolling [see the video] and Global [see the video] Exposure modes – FIND OUT MORE

  • Snapshot imaging capability
  • No distortion of fast moving images
  • Faster 3D / 4D microscopy – ease of synchronization
  • No dead time, no photon waste

Andor Zyla 5.5 sCMOS Camera



Andor’s Zyla 5.5 sCMOS camera offers high speed, high sensitivity imaging performance in a remarkably light and compact, TE cooled design. Zyla is ideally suited to many cutting-edge applications that push the boundaries of speed, offering sustained frame rate performance of up to 100 fps, faster with ROIs.

A highly cost-effective USB 3.0 version is available offering 40 fps and 1.2 e rms read noise, representing an ideal low light ‘workhorse’ upgrade camera solution for both microscopy and physical science applications, in either research or OEM environments.

Rolling and Global (Snapshot) Shutter readout inherent to Zyla 5.5 ensures maximum application flexibility. Global shutter to the in particular provides an important ‘freeze frame’ exposure mechanism that emulates that of an interline CCD, overcoming the transient readout nature of Rolling shutter mode.

The Andor GPU Express library has been created to simplify and optimize data transfers from camera to a CUDA-enabled NVidia Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline.

Key Specifications
Sensor Type Front Illuminated Scientific CMOS
Active Pixels 2560 x 2160 (5.5 Megapixel)
Sensor Size 16.6 x 14.0 mm (21.8 mm diagonal)
Pixel well depth (typical) 30,000 e
Pixel readout rate (MHz) 560 (280 MHz x 2 sensor halves) 200 (100 MHz x 2 sensor halves)
Read Noise (e-)
200 MHz
560 MHz
Rolling Shutter
Global Shutter
Maximum frame rate 40 fps @ full frame (USB 3.0)
100 fps @ full frame (Camera Link 10-tap)
Maximum Quantum Efficiency 60%
Dark current, e-
/pixel/sec @ 0°C
Readout modes Rolling Shutter and Global (Snapshot) Shutter
Maximum dynamic range 25,000:1
Photon Response Non-Uniformity (PRNU) < 0.5%
Pre-defined Region of Interest 2048 x 2048, 1920 x 1080, 1392 x 1040, 512 x 512, 128 x 128
Data range 12 bit and 16 bit
Interface options USB 3.0, Camera Link 10-tap
Features Benefits
1.2 e read noise Offers lower detection limit than any CCD.
Rolling and Global (Snapshot) shutter Maximum exposure and readout flexibility across all applications. Snapshot for ‘interline CCD mode’ freeze frame capture of fast moving/changing events.
Sub-microsecond inter-frame gap Global Shutter offers down to 100 ns inter-frame gap, ideal for PIV applications.
Industry Fastest Frame Rates 100 fps (full frame) sustained via Camera Link . Industry fastest USB 3.0 frame rates, 40 fps (full frame). Faster speeds with ROI.
5.5 megapixel sensor format and 6.5 μm pixels Delivers extremely sharp resolution over a 22 mm diagonal field of view; ideal for cell microscopy, astronomy and area scanning applications such as digital pathology and high content screening.
Dual-Gain Amplifiers Maximum well depth and lowest noise simultaneously, affording extended dynamic range of 25,000:1
12-bit and 16-bit modes 12-bit for smaller file size and absolute fastest frame rates through USB 3.0; 16-bit for full dynamic range.
Low dark current: 0.10 e/pix/s Extremely competitive optimized darkcurrent. Maintains low noise advantage across range of exposure conditions.
TE cooling to 0° C in 35 °C ambient Ideal for OEM integration into enclosed systems.
GPU Express Simplify and optimize data transfers from camera to Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline.
Compact and Light Ideal for integration into space restrictive set-ups. Perfect for OEM.
Hardware Timestamp FPGA generated timestamp with 25ns accuracy.
Dynamic Baseline Clamp Essential to ensure quantitative accuracy across the image area and between successive images of a kinetic series.
Spurious Noise Filter Real time FPGA filter that identifies and compensates for spurious high noise pixels.
Single window design Single input window with double AR coating ensures maximum photon throughput.
Comprehensive trigger modes and I/O Communication and synchronization within intricate experimental set-ups.