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Nanoscribe – Quantum X bio

The world’s most accurate 3D bioprinter

The Quantum X bio is an exceptionally capable, versatile bioprinter with the highest resolution available. Powered by Two-Photon Polymerization (2PP) and grounded in engineering excellence, the proprietary technology is customized and reimagined through the eyes of a biologist.

The light-based 3D bioprinter offers essential features such as precise temperature and humidity control, HEPA-filtered airflow and an optional connection for pre-mixed air/CO2. A variety of functionalized biomaterials can be used to unlock a new level of bioprinting and effectively accelerate innovation in tissue engineering, microbiology, materials engineering and biomedical devices.



Bring your ideas to life with the highest precision 3D printing


  • 3D bioprinter based on Two-Photon Polymerization
  • The bioprinting chamber creates a sterile environment with temperature and humidity control, and HEPA-filtered airflow with optional connection for pre-mixed air/CO2, ready to work with aqueous biomaterials and cells
  • Versatile system for microfabrication on a variety of substrates, e.g. cell culture dishes, microscope slides, glass and silicon wafers, and microfluidic chips
  • High-resolution printing process with feature sizes down to 1 µm and below (material dependent) for subcellular structures
  • Ready to explore live cell printing with custom bioresins
  • Set up of custom materials with automated calibration; printing parameters are found using print job templates for parameter sweep
  • Quick start and inspiration by Bioprinting Model Library
  • Touchscreen and remote control software for ease of use
  • Comprehensive support information and NanoGuide training videos
  • Rapid prototyping with the highest precision and design freedom in a straightforward workflow
  • Ideal for multi-user facilities: Modular system for a wide range of applications


Benchmark scores
Feature size control 1 down to 100 nm
Stitching-free part diameter up to 4,000 µm
Maximum scan speed 6.25 m/s divided by lens magnification
Live-cell printing viability > 90 %


General system properties
Printing technology Layer-by-layer 3D printing based on Two-Photon Polymerization (2PP)
Upright platform with Dip-in Laser Lithography (DiLL)
Substrates Microscope slides / microfluidic chips (3 x 1” / 76 x 26 mm)
Cell culture imaging dishes (35 mm or 50 mm)
Wafers from 1” to 8” (25.4 mm to 200 mm)
Glass, silicon, and further transparent, opaque materials, and coated/uncoated substrates
Photoresins Open system for custom materials
Hydrogels/Bioresins from Advanced BioMatrix, Cellink and BIO INX
Nanoscribe IP/IPX Photoresins (polymers)
Nanoscribe acrylate, PDMS and glass photoresins (biocompatible, ISO 10993-5)
Maximum print area 50 x 50 mm²

Given values may vary depending on the photoresin and structure geometry.
1 100 nm feature size control in x/y direction, valid only for certain photopolymers

1. Bioprinting Model Library

Benefit from a comprehensive library of STL models provided jointly by CELLINK and Nanoscribe. Instead of spending hours creating designs in CAD, simply select a design from our database, download it and customize it to your needs. The designs provided are inspired by biological and biomedical applications. The designs are scalable, so you can use them not only on the Quantum X bio but also on other bioprinters such as CELLINK’s BIONOVA X or BIO X6. This is your fast track to printing success.


2. DeScribeX

DeScribeX is a print job development software for creating custom 3D prints. The built-in import wizard can load STL files as a widely used 3D CAD format. Pre-installed software printing parameter presets are perfect starting points that guide you to a successful print in just a few steps. The export function makes it easy to transfer the print job to the Quantum X bio remotely.

Key feature Benefits
3D CAD model import wizard Intuitive workflow generates suitable print job files from standard STL files
Print parameter presets Ready-to-use preset parameters for optimal printing results right out of the box
Adaptive slicing For surface refinement and improved shape accuracy
Parameter sweep Easily find the perfectly matching print parameters for new materials and applications
Integrated Development Environment (IDE) Experts can create and modify print files (GWL) for custom and sophisticated printing tasks
3D preview and printing simulation What you see is what you print! DeScribeX displays parameters such as print time, scan speed or laser power and simulates the entire printing process in detail


3. Touchscreen

Control and monitor the system with the Quantum X bio front panel touchscreen. It guides you to a successful print in just a few steps. Select your print project, then load your substrate and start printing.

Key feature Benefits
Three live cameras Monitor the printing process online from three perspectives and stay informed about the current status of your print job
Stage control in x, y and z direction Move the stage to any position on the substrate to define your print area
User-friendly print setup Select resin and substrate, and start the print job with a single click
Project list Keep track of the entire print job history
Automatic interface finder Identify the interface of the substrate with submicrometer accuracy, for standard and custom materials.
Custom materials support Configure and manage custom materials, including automated calibration routines
3D rendered preview A 3D simulation preview shows substrate and objective lens with automatic collision detection for better overview and safe operation
Easy to align Double-tap on the screen to print at the right spot in microfluidic channels or patterned substrates with the “Tap to align” feature


4. nanoConnectX

nanoConnectX is the remote access software for the Quantum X systems. It brings all the functions and display capabilities of the touchscreen to any computer connected online.

Key feature Benefits
Remote access to the system Connect Quantum X bio to your computer, wherever you are
Use all features of the touchscreen Prepare, control and monitor your print jobs from anywhere
Upload and download print jobs and reports Access print-related files directly from your computer