LightHUB Plus Laser Light Engines

The LightHUB+® Plug&Play laser light engines can be equipped with up to six DPSS or diode lasers of different wavelengths in a compact and rugged design. Wavelengths between 375nm and 1550nm and optical output powers up to 300mW per laser line are possible. The LightHUB+ can be upgraded by the end-user from 1…6 wavelengths easily. Pre-assembled upgrade-kits consisting of the laser head. optical combiner block and an interface card can be installed at any time. The fiber output can be equipped with Single-Mode, polarization-maintaining fibres or Mult-Mode fibers with various ourput connectors or collimated beam diameters starting from 0.7mm. Six individual Analog and Digital Modulation Inputs as well as a RS-232 and USB Interface allow easy Integration Input control environemts. The system is designed to be both passively or actively cooled. By mounting it on a optical table or thicker breadboard, passive cooling is possible. If the system should be operated in a free-standing desk-top use, the optional active cooling unit with temperature controlled fans can be attached underneath.

Andor Sona-6 Extreme

Sona-6 Extreme: Extreme Sensitivity & Speed

Sona is Andor’s latest high performance sCMOS camera series, specifically for life science imaging applications. Sona-6 Extreme features a back-illuminated sensor with 95% QE and a 6.5 μm pixel size. This sensor format provides a perfect balance of sensitivity, speed, and resolution. Exceptionally flexible, and ideally suited to 40x and 60x magnification and today’s microscope port sizes. Compatible with SRRF-Stream+ Super-resolution.

NEW & IMPROVED Capture the dynamics of life with Sona-6 Extreme

✔️ Accelerated speeds: new high-speed mode accelerates speeds to 135 fps (full frame) via CoaXPress to capture the fastest cellular processes.
✔️ Improved sensitivity: the noise floor has been reduced by 25%. Sensitivity is thus improved for better detection of the weakest signals.
✔️ Enhanced image quality: PRNU has been reduced by 25% under low light conditions.
✔️Python ready – Updated camera SDK integrates a Python wrapper for speedy integration.

Configurable Raman Probe

Our Configurable Raman Probe is available in both single or dual wavelength and is optimized to mate with IPS multimode fiber coupled lasers to offer higher throughput and low stray light.

Andor ZL41 Wave sCMOS

Andor’s ZL41 Wave physical sciences sCMOS camera platform delivers sheer excellence in speed, sensitivity, dynamic range and resolution, with comprehensive imaging and spectroscopy functionalities. Building upon the strengths of the original Zyla sCMOS series, the cost-effective, compact, thermoelectrically cooled design of ZL41 Wave benefits from a reengineered and enhanced sensor chamber and is supported within a wide range of physical science software environments, integrating perfectly into any optical laboratory or observatory setting.

 

  • Up to 82% QE
  • < 1 e- read noise
  • Up to 100 fps
  • 32-bit binning mode
  • Spectroscopy modes
  • Operate down to -20°C ambient

LuxX+ Diode Laser Series

LuxX+® Compact high-performance diode laser modules for biotech and industrial applications

The Omicron LuxX+® Laser Series offers high-perfomance at a compact design. A broad variety of wavelengths and single-mode emission up to 500mW cover a wide range of applications. Easy integration into existing or future designs is assured by versatile input signal types. The USB2.0 and the RS-232 interface support deep integration of the lasers into the application´s process.

Single-Mode Digital L-Type Module with Optical Isolator

The wavelength stabilized Single-Mode Digital L-Type Module with Optical Isolator can be used in applications such as metrology/interferometry, remote sensing, Raman spectroscopy, direct-diode frequency doubling, and fiber laser seeding.

Multi-Mode Digital U-Type Module

Our proprietary  multi-spatial-mode wavelength stabilized Multi-Mode Digital U-Type Module features high output power with ultra-narrow spectral bandwidth.

Multi-Mode Digital M-Type Module

Our proprietary Wavelength Stabilized Multi-Mode Digital M-Type Module features high output power with narrow spectral bandwidth. The laser’s stabilized peak wavelength remains “locked” regardless of case temperature (10 to 35 deg. C).  Devices can be spectrally tailored to suit application needs and offer side mode suppression ratios (SMSRs) better than 40 dB, thereby providing extremely high signal to noise ratio and making these sources ideal for Raman spectroscopy and pump laser applications.

Tomocube HT-X1 Holotomography

By capturing the intrinsic refractive index (RI) of cells using a low level of light intensity, Holotomography has emerged as a unique solution for live cell imaging that surpasses the compromise between obtaining high image quality and maintaining healthy cells.

Empowering your exploration. Redefining the limits.

 

The lastest generation of Holotomography – Tomocube HT-X1 – utilizes a low-coherence light source. This groundbreaking advancement unlocks label-free 3D and 4D quantitative live cell imaging on diverse multi-well plates with improved resolution and free of laser-induced speckle noise.

The new system works well with a wide range of biological samples, including confluent cell sheets and thick specimens. It provides not only high-content 3D visualization but also quantitative data for individual cells and their intracellular structures, such as the volume, surface area, and dry mass.

 

Multiplying Knowledge from 2D to 4D and Beyond

Observations of cellular morphology and activity are typically based on labeling of target molecules. These methods are invasive, affect the nature of the target molecules and potentially interfere with their biological relevance. In addition, these forms of label are not effective in providing quantitative information. The tools used to visualize labels are generally damaging to cells as often laser-based illumination is used to excite fluorochromes which in turn causes phototoxic damage to the cells.

The “holy grail” of imaging is to visualize cells without labeling to ensure the cells behave and grow normally. Holotomography (HT) does this by capturing the intrinsic light scattering properties of cellular materials using very low levels of light intensity, just enough to allow the light to pass through the cell. In doing so, the refractive index (RI) information of structures within the cell can be collected and selectively pseudo-colored to reveal the cell and its organelles.

In capturing the RI distribution, the Tomocube HT-X1 Holotomography can also provide quantitative data in 3D such as the volume, surface area, and dry mass of cells and their intracellular structures.

 

Correlative HT to FL

 

Holotomography and Fluorescence

Fluorescence