Archives: Product

Single-Mode Digital L-Type Module with Optical Isolator

The wavelength stabilized Single-Mode Digital L-Type Module with Optical Isolator can be used in applications such as metrology/interferometry, remote sensing, Raman spectroscopy, direct-diode frequency doubling, and fiber laser seeding.

Multi-Mode Digital U-Type Module

Our proprietary  multi-spatial-mode wavelength stabilized Multi-Mode Digital U-Type Module features high output power with ultra-narrow spectral bandwidth.

Multi-Mode Digital M-Type Module

Our proprietary Wavelength Stabilized Multi-Mode Digital M-Type Module features high output power with narrow spectral bandwidth. The laser’s stabilized peak wavelength remains “locked” regardless of case temperature (10 to 35 deg. C).  Devices can be spectrally tailored to suit application needs and offer side mode suppression ratios (SMSRs) better than 40 dB, thereby providing extremely high signal to noise ratio and making these sources ideal for Raman spectroscopy and pump laser applications.

Tomocube HT-X1 Holotomography

By capturing the intrinsic refractive index (RI) of cells using a low level of light intensity, Holotomography has emerged as a unique solution for live cell imaging that surpasses the compromise between obtaining high image quality and maintaining healthy cells.

Empowering your exploration. Redefining the limits.

 

The lastest generation of Holotomography – Tomocube HT-X1 – utilizes a low-coherence light source. This groundbreaking advancement unlocks label-free 3D and 4D quantitative live cell imaging on diverse multi-well plates with improved resolution and free of laser-induced speckle noise.

The new system works well with a wide range of biological samples, including confluent cell sheets and thick specimens. It provides not only high-content 3D visualization but also quantitative data for individual cells and their intracellular structures, such as the volume, surface area, and dry mass.

 

Multiplying Knowledge from 2D to 4D and Beyond

Observations of cellular morphology and activity are typically based on labeling of target molecules. These methods are invasive, affect the nature of the target molecules and potentially interfere with their biological relevance. In addition, these forms of label are not effective in providing quantitative information. The tools used to visualize labels are generally damaging to cells as often laser-based illumination is used to excite fluorochromes which in turn causes phototoxic damage to the cells.

The “holy grail” of imaging is to visualize cells without labeling to ensure the cells behave and grow normally. Holotomography (HT) does this by capturing the intrinsic light scattering properties of cellular materials using very low levels of light intensity, just enough to allow the light to pass through the cell. In doing so, the refractive index (RI) information of structures within the cell can be collected and selectively pseudo-colored to reveal the cell and its organelles.

In capturing the RI distribution, the Tomocube HT-X1 Holotomography can also provide quantitative data in 3D such as the volume, surface area, and dry mass of cells and their intracellular structures.

 

Correlative HT to FL

 

Holotomography and Fluorescence

Fluorescence

Nanoscribe- Quantum X shape

Nanoscribe- Quantum X shape – Tomocube HT-X1 Holotomography – Quantum X shape is a truly capable multi-talent. Based on Two-Photon Polymerization (2PP).
     

Fastest and most accurate 3D printer for high-end microfabrication tasks

Quantum X shape is a truly capable multi-talent. Based on Two-Photon Polymerization (2PP), the 3D laser lithography system combines proprietary 3D printing technologies that make it the optimal tool for rapid prototyping and wafer-scale batch processing of virtually any 2.5D and 3D shape with submicron precision and accuracy.

 

Reshaping precision.

As the second high-resolution two-photon lithography system in the industry-proven Quantum X platform, Quantum X shape offers high-resolution 3D Microfabrication capabilities with unmatched precision, next to Nanoscribe’s breakthrough technology of Two-Photon Grayscale Lithography (2GL ®) for surface patterning. The new Quantum X shape’s superior precision relies on the highest voxel modulation rate in class, and an extremely fine address grid, allowing for sub-voxel size shape control. In addition, you benefit from the 2GL voxel tuning capability for 2.5D structures with stunningly smooth, accurately shaped, or micropatterned surfaces.

 

Reshaping output.

Quantum X shape is the ideal additive manufacturing tool for rapid prototyping of application designs in biomedical devices, microoptics, microelectromechanical systems (MEMS), microfluidics, surface engineering and many more. Wafer handling capabilities make wafer-scale batch processing and small series production of 3D microparts easier than ever.

 

Reshaping usability.

Control your print job via the device’s integrated touchscreen. Keep an eye on your two-photon lithography system even from the office and in multi-user configurations via nanoConnectX. And benefit from industrial standards and time-efficient wafer batch production.

 

Technical features in brief
  • Rapid prototyping with highest precision and design freedom along a straightforward workflow
  • Industry-proven platform for wafer-scale batch processing
  • 200 typical mesoscale structures printable overnight
  • Print volumes up to 30 cubic centimeters in one pass with the new XLF Print Set
  • Broad range of application-specific and universal printing materials
  • Open direct laser writing system for custom-made and third-party materials

Nanoscribe – Quantum X align

Highest resolution 3D printer with A2PL® technology for nanoprecise alignment

The Aligned 2-Photon Lithography (A2PL®) system Quantum X align enhances Nanoscribe’s field-proven 3D Microfabrication technology based on Two-Photon Polymerization (2PP) by adding high-precision alignment capabilities for highly accurate placement of printed structures. With A2PL freeform microoptics can be printed precisely aligned to the optical axes of fibers or photonic chips with submicron accuracy using this highest resolution 3D printer with nanoprecision aligned 3D printing capabilities. Produce efficient optical interconnects for photonic integration and photonics packaging or miniaturized imaging optics, e.g. for minimally invasive endoscopy.

 

Technical features in brief
  • High-performance 3D Microfabrication by Aligned 2-Photon Lithography (A2PL)
  • 3D printing on fibers: Precisely aligned printing on the facets of optical fibers based on fiber core detection
  • 3D printing on chips: Precisely aligned printing on the surface or facet of chips based on 3D substrate topography mapping
  • 3D alignment: Automatic detection and compensation of substrate tilt in 3 rotation axes
  • Smart slicing for high-speed microfabrication

Nanoscribe – Quantum X bio

The world’s most accurate 3D bioprinter

The Quantum X bio is an exceptionally capable, versatile bioprinter with the highest resolution available. Powered by Two-Photon Polymerization (2PP) and grounded in engineering excellence, the proprietary technology is customized and reimagined through the eyes of a biologist.

The light-based 3D bioprinter offers essential features such as precise temperature and humidity control, HEPA-filtered airflow and an optional connection for pre-mixed air/CO2. A variety of functionalized biomaterials can be used to unlock a new level of bioprinting and effectively accelerate innovation in tissue engineering, microbiology, materials engineering and biomedical devices.

 

 

Bring your ideas to life with the highest precision 3D printing

 

Nikon AX / AX R with NSPARC

Improving on Perfection

Confocal microscopes have been commercially available now for over 25 years. How can newer iterations of a fundamentally simple instrument continue to innovate? What changes can redefine how a confocal is used, and what data can be collected? Introducing the Nikon AX/AX R Confocal Microscope System, our 10th generation point scanning confocal, giving you more of everything: Leveraging Artificial Intelligence (AI), expanding the number of colors, improving pixel density, sensitivity and speed.

These are significant additions in terms of expanding the range of experiments possible with a point scanning confocal, while increasing the usability and functionality of the instrument, all in a modular and upgradable platform.

Nikon AX is the new standard in confocal imaging.

 

Igniting New Confocal Imaging Potential

The newly developed Nikon Spatial Array Confocal (NSPARC) detector utilizes an ultra-low noise detector array to collect a two-dimensional image at each scanned point. This method of image scanning microscopy (ISM) improves signal-to-noise ratio by increasing the available signal level while simultaneously allowing imaging with lower excitation power.

Single-photon sensitivity and array detection extend the capabilities of the AX system by revealing unseen details in every image, while array detection pushes the boundaries of resolution beyond the theoretical limits.

PicoQuant- Single Photon Counting Confocal Microscope – Luminosa

Explore new paths in confocal microscopy

Luminosa pairs highest data quality with remarkably simple day-to-day operation. It easily integrates into any researcher’s toolbox and becomes a time-efficient, reliable companion for scientists starting to explore the use of time-resolved fluorescence methodologies as well as for experts wanting to push the limits. Truly a microscopy system that everybody can rely on.

  • Quality and precision you can trust
  • Save time and simply focus on your samples
  • Advanced flexibility